Amide Bond
Amide bond is a specific type of covalent chemical bond. In organic chemistry, it is formed by the condensation reaction between a carboxylic acid and an amine.
When the amide group occurs in the main chain of a protein, it’s called a peptide bond. An isopeptide bond occurs in a side chain. Peptide bonds are essential in forming proteins. They link amino acids in a specific sequence.
Amides
Amide is an organic compound. It is also known as an organic amide or carboxamide. It contains a carbonyl functional group that is bonded with a nitrogen atom. The simplest amide is a derivative of ammonia NH3, here one hydrogen atom is replaced by an acyl group.
In this article, we will define Amide, its types, structures, along with its properties.
Amide Functional Group |
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Nomenclature |
Amides are named by replacing the -oic acid or -ic acid ending of the parent carboxylic acid with -amide. For example, ethanoic acid becomes ethanamide |
Nature |
Neutral or very weak acids |
Appearance |
White crystalline solid |
Odor |
Ethanamide, a simple amide, is said to smell like mice. |
Density |
Generally, they are denser than water. |
Melting Point |
Amides have high melting points.
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Boiling Point |
Amides have high boiling points due to the presence of strong hydrogen bonds.
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Solubility |
Soluble in Water |
Table of Content
- What is Amide?
- Amide Structure
- Classifications of Amides
- Amide Bond
- Synthesis of Amide
- Amide Vs. Amine