Artemisinin Combination Therapy (ACT)
Artemisinin Combination Therapy (ACT) is a treatment for malaria that combines artemisinin with other antimalarial drugs to enhance efficacy and reduce resistance.
- Artemisinin combination therapy Provide rapid clearance of parasite providing relief.
- This therapy is recommended by WHO as the first line treatment for uncomplicated malaria.
- Various ACTs are available namely artemether-lumefanterine and artesunate-mefloquine that provides flexibility in treatment based on regional resistance patterns and patent tolerance for a regional parasite.
Uses of Artemisinin – Structure and Mode of Action
Artemisinin is a bioactive compound obtained from the leaves of a sweet wormwood plant known as Artemisia annua. It is a sesquiterpene endoperoxidase. Understanding Artemisinin uses and Artemisinin structure is crucial for appreciating its role in medicine.
In this article, we will cover Artemisinin mechanism of action, derivatives, and biological sources along with Artemisinin Combination Therapy in detail.
Table of Content
- What is Artemisinin?
- Chemical Nature of Artemisinin
- Structure of Artemisinin
- Derivatives of Artemisinin
- Isolation and Extraction of Artemisinin
- (a) Extraction
- (b) Isolation & purification
- Uses of Artemisinin
- Artemisinin Mechanism of Action
- Challenges and Concerns Related to Artemisinin
- Artemisinin Combination Therapy (ACT)