DNA Damage
DNA Damage refers to any alteration in the normal structure of DNA, the genetic material that carries the genetic instructions for the development, functioning, growth, and reproduction of all living organisms. DNA damage can occur due to various external and internal factors, and if not repaired properly, it can lead to genetic mutations, and cell dysfunction, and can contribute to diseases such as cancer. Various factors, including exposure to radiation, chemicals, and errors during DNA replication, can cause DNA damage.
DNA Repair – Damage & Types of Repair
DNA Repair is an important process in which cells recognize and rectify damage to the DNA molecules that make up their genetic material. DNA Repair is an important process as it protects cells from environmental damage and in the ageing process. In human beings, metabolic activities and environment-related factors such as UV rays contribute to DNA damage, resulting in 1 million lesions per cell every day these can damage the structure of the DNA molecule and if they are not repaired, then damage can cause mutations, cellular dysfunction, cancer, and ageing. The preservation of genetic integrity is most important for the survival of an organism and the efficiency of repair mechanisms is crucial for the maintenance of the stability.
Table of Content
- What is DNA Repair?
- DNA Repair and Damage
- DNA Damage
- Sources of DNA Damage
- Types of DNA Repair Mechanisms
- Significance of DNA repair
- Conclusion