Samples Questions on Friedel-Crafts Reactions
Example 1. How are ethers formed by Friedel-crafts reaction?
Solution:
Formation of Ether by Friedel-crafts reaction can be formed through acylation or alkylation of anisole. The mechanism of alkylation and acylation of anisole by Friedel-crafts reaction are as follows:
Friedel-crafts Alkylation of Anisole
The Friedel Craft alkylation of anisole is given as:
Friedel-crafts acylation of Anisole
The Friedel craft acylation of anisole is given as follows:
Example 2: Show the Friedel-crafts acylation and alkylation reaction of Chloro-benzene.
Solution:
The Friedel-crafts alkylation of chloro-benzene is as follows:
Here, CH3Cl is a halogen and catalyst(AlCl3) speeds up the process of reaction. It is reacted with chlorobenzene to give two products.
As, the halogen can be attacked by both para- and ortho-position, two products are formed.
The Friedel-crafts acylation reaction of chlorobenzene is:
Similarly, here, chlorobenzene is reacted with acetyl chloride, which undergoes a reaction with a catalyst (Anhydrous AlCl3) and gives two products. One with acetyl attached on ortho-position, and the other with para-position.
Friedel–Crafts Reaction
Friedel–Crafts Reaction was discovered by French chemist Charles Friedel and the American chemist James Crafts in the late 19th century. There are two main types of Friedel-Crafts reactions, namely, Friedel-Crafts Alkylation and Friedel-Crafts Acylation.
In this article, we will read in detail about the Friedel Craft Reaction, its types, mechanisms, and examples.