Types of Blood Group System

There are mainly two types of blood group systems. Combining both will make the complete characteristic of any blood type. These types of blood depend upon the Antigen available on the RBCs. They are:

  1. ABO Group System
  2. Rh Group System

ABO Group System

The ABO blood group system divides the blood into four types. They are A, B, AB & O types of blood. In A type of blood, there are Antigen A is present. For blood B there are B antigens present. For AB blood there are both A & B types of antigen are present. And for O type of blood there no antigens are present. Now, there is another protein structure which is known as the Antibody. This Antibody is present in the serum of the blood. They are not situated on the surface of RBCs.

Rh Group System

This is the 2nd most significant blood group system. This type of system was first discovered in the 1940s in Rhesus Monkey. There is mainly one Antigen that determines the type of the blood group. The antigen is known as the D antigen. Though there are many other antigens present in the Rh system. But the D antigen plays a major role here. Rh stands for the “Rhesus”.

Rh Blood Group System

Blood is the main component of our cardiac system. It is the main body fluid that helps to circulate the necessary substances throughout the body. It delivers the nutrients, oxygen & other necessary components to every cell of the body. Now, blood comprises blood cells. There are Red Blood Cells, White Blood Cells, etc. White Blood Cells are responsible for the immune system of the body. Whereas,  Red Blood Cells are responsible for the types of blood groups. These blood groups help us to identify human blood in a very efficient way. Also, these blood groups help us to aware before any blood transplant. So, it is very important to know the blood group systems. These blood groups are divided by the presence of antigens. Antigens are those proteins that are situated above the RBCs. The presence of a particular antigen establishes a particular type of blood.

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Types of Blood Group System

There are mainly two types of blood group systems. Combining both will make the complete characteristic of any blood type. These types of blood depend upon the Antigen available on the RBCs. They are:...

Discovering the Rh Factor

The Rh factor was discovered through some experiments performed by a group of scientists. They took the RBCs from the Rhesus Monkey & injected those to the blood of small animals like rabbits. They found that those blood reacted to each other & coagulated. Then Scientists found that there is something in the RBCs of the Rhesus Monkey that triggers the antibody of the rabbit to react with each other. This same thing happened to all the monkeys....

Types of Rh Factor

Positive Rh: If the D antigen is present in the RBCs of a human, then it will call as Positive Rh (+ve) Negative Rh: If the D antigen is not present in the RBCs of a human or present in a relatively low quantity, then it will call as Negative Rh (-ve)...

Types of Antigens Present in Rh Factor

Scientists discovered till now 50+ antigens in the Rh factor. Though among them only five antigens are important. Among the five antigens, the D antigen is the most important in humans. Important antigens are:...

Composition of the Rh Factor

Rh factor is not an Anatomical structure. Thus it can’t have a solid structure. It is completely made with protein. It is situated on the surface of the RBCs. It is often called 12 Pass Membrane Protein. As it almost cross the RBC surface 12 times. Thus, it has six curved faces outside of the RBC & six curved faces inside of the RBC. Among them in the first outer curve, their will D antigen present. As this is the strongest antigen that is why it is situated in front of the RBC. The C/c antigens (Capital & Small C) are situated on the second outer curve. And the E/e antigens (Capital & Small E) are situated on the fourth outer curve....

Importance of Rh Factor

The importance of the Rh factor is limitless in science. While donating blood to a patient it is important to know their Rh group previously. Otherwise, there will be a huge problem if some different type of blood is transmitted. Also, it is important that it involve in the development process of the baby in the mother’s womb. Any type of problem that happened with the Rh blood group system can harm the baby. That is why before every operation doctors first take care of the Rh blood group availability. Different types of transplants can cause damage. Also, it is so important that different types of Rh group exposure to an individual body can change his Rh group system....

RHD Polymorphism

Polymorphism is a trait that is inherited from the parents of individuals. Every process which is influenced by inheritance & heredity is known as polymorphism. Polymorphism sometimes acts as a positive function & sometimes acts as a negative function. Polymorphism is a process where the trait of the mother & traits of the father is being combined. After combination a new baby takes birth. As this combination completely happens in a random form, sometimes it causes a problem. This leads to different diseases in a newborn baby. Or sometimes it can lead to a disease in adulthood....

Awareness of Rh Factor

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Hemolytic Disease & History of Disease

Hemolytic Disease is generated in a baby when a Rh+ mother & an Rh- father gives birth to a baby. This can also happen in reverse order also. Like if the mother is Rh- & father is Rh+ then also this type of disease can visualize. The main reason for this disease is that when the Rh factor of the mother is reverse of the Rh factor of the baby, this disease is visualized. In such cases, the mother’s body’s immune system defines the baby as an antigen. It starts producing the antibody against it. Hence, it can damage the growth of the baby....

Symptoms of Hemolytic Disease

Hemolytic Disease provides many symptoms. During the pregnancy or after birth it can show the symptoms to the baby. Mainly during the pregnancy period, a bunch of symptoms can observe. Some of them are...

FAQs on Rh Blood Group system

Question 1: Do Rh Factors inherited?...