What is Arthus Phenomenon?
The Arthus phenomenon or arthus reaction is an immunological reaction that causes localised tissue damage due to immune complex deposition in small blood vessels (arteries). This deposition occurs especially in the skin and joints, causing inflammation and tissue damage in the long term.
The Arthus phenomenon symptoms ranges from localised discomfort to tissue necrosis. It is a rare condition, yet crucial to understand since it has complex consequences in both clinical practice and immune-mediated reaction research.
Arthus Phenomenon
Arthus phenomenon, named after the French immunologist Nicolas Maurice Arthus, is an uncommon immune response that causes localised damage to the tissue. Arthus phenomenon results from the deposition of the immune complex. This condition happens when an antigen is repeatedly administered resulting in an exaggerated immunological response.
In this article, we will learn about the Arthus phenomenon, its mechanisms, examples, and management, which is critical for physicians and researchers in addressing the condition.
Table of Content
- What is Arthus Phenomenon?
- Arthus Reaction Mechanism
- Arthus Reaction Symptoms
- Examples of Arthus Reaction
- Diagnosis of Arthus Phenomenon
- Treatment of Arthus Phenomenon
- Research and Future Directions
- Arthus Reaction Vs Serum Sickness