What is Chloroquine?

Chloroquine is a medication used to prevent and treat malaria, a mosquito-borne infectious disease caused by Plasmodium parasites. Its mechanism involves accumulation within the parasite’s acidic digestive vacuole, disrupting essential metabolic processes. Chloroquine is also used in the treatment of certain autoimmune diseases like rheumatoid arthritis and lupus erythematosus. However, widespread resistance to chloroquine among malaria parasites has limited its effectiveness in certain regions. Common side effects include gastrointestinal disturbances and ocular toxicity, necessitating careful monitoring during treatment.

Chloroquine

Chloroquine, a quinoline derivative, is a medication primarily used to prevent and treat malaria by disrupting the parasite’s ability to metabolize haemoglobin. Its mechanism involves accumulating in acidic compartments of parasites, inhibiting heme detoxification, and ultimately leading to parasite death.

Chloroquine is also prescribed for autoimmune diseases like rheumatoid arthritis due to its anti-inflammatory properties. Understanding chloroquine structure and doses is crucial for comprehending its mechanism of action in treating diseases. In this article, we will study chloroquine, its structure, its mechanism of action and chloroquine phosphate in brief.

Table of Content

  • What is Chloroquine?
  • Structure of Chloroquine
  • Mechanism of Chloroquine of Action
  • Chloroquine Dose
  • Uses of Chloroquine
  • Side Effect of Chloroquine
  • Chloroquine Phosphate

Similar Reads

What is Chloroquine?

Chloroquine is a medication used to prevent and treat malaria, a mosquito-borne infectious disease caused by Plasmodium parasites. Its mechanism involves accumulation within the parasite’s acidic digestive vacuole, disrupting essential metabolic processes. Chloroquine is also used in the treatment of certain autoimmune diseases like rheumatoid arthritis and lupus erythematosus. However, widespread resistance to chloroquine among malaria parasites has limited its effectiveness in certain regions. Common side effects include gastrointestinal disturbances and ocular toxicity, necessitating careful monitoring during treatment....

Structure of Chloroquine

Chloroquine adopts a specific three-dimensional arrangement in space due to the spatial orientation of its atoms and functional groups. This three-dimensional structure is important for its interaction with biological targets and pharmacological activity....

Mechanism of Chloroquine of Action

The mechanism of chloroquine involves its ability to interfere with various processes in the Plasmodium parasites, ultimately leading to their death. Mechanism of Chloroquine is explained below:...

Chloroquine Dose

Chloroquine Dosage is given below:...

Uses of Chloroquine

The uses of chloroquine are:...

Side Effect of Chloroquine

Side effect of chloroquine includes:...

Chloroquine Phosphate

Chloroquine phosphate is used to treat malaria and certain autoimmune diseases. It is a synthetic antimalarial drug derived from quinine. Its chemical formula is C18H26ClN3•2H3PO4•H2O, indicating its molecular composition....

Conclusion: Chloroquine

Chloroquine, a 4-aminoquinoline derivative, disrupts the parasite’s ability to detoxify heme by inhibiting heme polymerase. It’s primarily used in the treatment and prevention of malaria and certain autoimmune diseases like rheumatoid arthritis and lupus erythematosus. Side effects include gastrointestinal disturbances, skin reactions, and retinopathy with long-term use, necessitating caution and regular monitoring. Its mechanism involves accumulation in acidic vacuoles within the parasite, raising pH and interfering with essential processes....

FAQs on Chloroquine

What is Chloroquine Used For?...